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On the heels of the success of GLP-1s like Ozempic, other peptide treatments are flooding the marketplace—and advertising spaces. But even as the Trump administration’s FDA discusses approving more treatments and the businesses selling them proliferate, many peptides are sitting in a legal and medical gray area. So how real - and safe - is this peptide hype?

Guest: Kate Knibbs, senior writer at WIRED.

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Podcast production by Rob Gunther, Evan Campbell, Madeline Thames-Ducharme and Patrick Fort.

Paige Osburn is the senior supervising producer of What Next and What Next TBD.
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The US can’t leave Iran in charge of the Strait of Hormuz, but it can’t wrestle control away without committing ground troops—but it also can’t keep going on like this. So where does that leave everyone?

Guest: Josh Keating, senior correspondent covering foreign affairs at Vox.

Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.

Podcast production by Rob Gunther, Evan Campbell, Madeline Thames-Ducharme and Patrick Fort.

Paige Osburn is the senior supervising producer of What Next and What Next TBD.
Hosted on Acast. See acast.com/privacy for more information.

In the wake of the success among members of the Democratic Socialists of America, The Atlantic’s Jonathan Chait has turned in a series of articles that call the group anti-democratic, against the Democratic Party, and unnecessary or even a hindrance to accomplishing policy goals like universal health care. On the other hand, he thinks DSA member Zohran Mamdani is doing a pretty good job as mayor so far.

So what’s at the root of Chait’s problem with the DSA? And what policy position is he completely on board with?

Guest: Jonathan Chait, staff writer at The Atlantic.

Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.

Podcast production by Rob Gunther, Evan Campbell, Madeline Thames-Ducharme and Patrick Fort.

Paige Osburn is the senior supervising producer of What Next and What Next TBD.
Hosted on Acast. See acast.com/privacy for more information.

In the immediate aftermath of Charlie Kirk’s murder, the NFL was holding moments of silence, Ezra Klein was waxing about how he was ‘practicing politics the right way,” and criticizing Kirk online could get you fired. Now, as the trial of Tyler Robinson, Kirk’s alleged killer, begins, something has replaced that reverence.

Guest: Will Sommer, senior reporter for the Bulwark and writer of False Flag, a newsletter about the online culture and communities now running our country.

Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.

Podcast production by Rob Gunther, Evan Campbell, Madeline Thames-Ducharme and Patrick Fort.

Paige Osburn is the senior supervising producer of What Next and What Next TBD.
Hosted on Acast. See acast.com/privacy for more information.

In 1867, an 8-year-old girl named Elizabeth Turner became the epicenter of a legal battle that would help define what freedom really meant after the Civil War. Days after Maryland abolished slavery, her former enslaver had her re-indentured under a sham "apprenticeship" law used to seize Black children. Elizabeth’s mother—and thousands of other parents—refused to accept it.

In this second episode of By the People, legal scholar Lyle Cherneff guides Dahlia Lithwick and Mark Joseph Stern through a Union Army general's archive of letters that documented the plight of Black parents who petitioned, marched, and filed habeas corpus claims to win their children back. These parents read the new constitutional guarantees of freedom for themselves, and demanded they be enforced, long before any Supreme Court told them what those words meant.

The resulting case, In re: Turner, helped end the practice of racialized child "apprenticeship" and shaped the meaning of the 13th and 14th amendments. But the parents who fought for it were nearly written out of the story. In this episode, we seek to restore that record, tracing a direct line from their fight to ordinary Americans’ resistance to ICE raids today.

By the People is Slate’s end-of-term project exploring how ordinary Americans have shaped the meaning of the Constitution outside the Supreme Court. You can read the full package of articles accompanying this series at slate.com/bythepeople

The justices publish their opinions a few dozen times a year. Dahlia and Mark share theirs every week. Slate Plus gets you all of it: Amicus ad-free with a weekly bonus segment, and no paywalls anywhere on Slate. Join now. Visit slate.com/amicusplus to get access wherever you listen.

You can subscribe directly from the Amicus show page on Apple Podcasts and Spotify.
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