Biomedical Frontiers: Stories with Innovators in Healthcare

• Digital Mental Health - the Future of Managing Anxiety and Depression with Dr. Bethany Teachman

  How do we tackle the rising epidemic of anxiety with tools that actually scale? Why aren’t traditional therapy models enough? And how can digital technologies like mobile sensing and cognitive bias modification help close the treatment gap in mental health?In this episode of Biomedical Frontiers, host Dasha Tyshlek sits down with Dr. Bethany Teachman, Professor of Psychology and Director of Clinical Training at the University of Virginia, to explore how digital mental health tools are being designed and tested to meet people where they are.Dr. Teachman is the founder of MindTrails, a suite of app-based tools to help individuals reduce anxious thinking, and co-leads the UVA TYDE initiative (Thriving Youth in a Digital Environment). She brings a unique perspective as both a clinician and innovator developing tools rooted in science but built for the real world.Topics Discussed:Why anxiety and depression are rising—and why therapy alone isn’t enoughHow mobile sensing and AI can detect anxiety through physiological, social, and environmental cuesHow MindTrails helps people shift negative thinking patternsWhat it takes to co-develop ethical and effective tech with engineersChallenges of building digital interventions people actually useThe unique value a clinician brings to tech innovationResources Mentioned:🔹 MindTrails: https://mindtrails.virginia.edu/science.html🔹 UVA TYDE: https://tyde.virginia.edu/🔹 Research Paper: Mobile Sensing and Anxiety Detection🔹 Research Paper: CBM-I Digital Intervention PreprintFollow Dr. Bethany Teachman:Lab Website: https://teachman.orgEmail: [email protected]: https://www.linkedin.com/in/bethany-teachman-b78558236/Follow Biomedical Frontiers for more:📸 Instagram: @biomedicalfrontiers 🔗 LinkedIn: https://www.linkedin.com/company/uvacoulter 📧 Reach us: [email protected] this podcast? Write to us with feedback or guest recommendations!Production Team:Director & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.comExecutive Producer: David Chen, Managing Director & Instructor of Engineering DesignSenior Producer: Hannah Moore, Associate Director, UVA CoulterDesign Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.comProduced on behalf of: Wallace H. Coulter Center for Translational Research at University of Virginia

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• Improving Rural Health: Medical Devices That Increase Health Access With Dr. Aileen Helsel

  Can medical devices improve patient care in rural healthcare systems? In this episode, Dr. Aileen Helsel, Director of Innovation at Carilion Clinic, shares how her team of engineers works with Carilion’s clinical teams to develop new medical devices that solve unique challenges in rural settings.Rural patients often travel long distances for care - making management of time sensitive emergencies and recurring visits for chronic conditions particularly challenging. Dr. Helsel highlights three projects: a wearable lymphedema therapy device, an early detection system for ventriculoperitoneal shunt failures, and a cardiac surgery arm positioning device. Each of these devices was conceptualized at the bedside (or in the operating room) and brought to life with the expertise and passion of a physician.Dr. Helsel began her career as a research scientist at Washington State University before transitioning to technology transfer in the licensing and ventures team at WSU. She was always looking for a greater impact. Now, as Director of Innovation at Carilion Clinic, she partners with physicians, nurses, and therapists on the front lines to help solve their most pressing challenges. Aileen shares how her team collaborates with a human factors group and a simulation center to test prototypes in realistic settings. Dr. Helsel believes that solving targeted problems in rural healthcare can yield scalable solutions that benefit the broader medical community.Love this podcast? Write to us with ideas, feedback, and guest recommendations at [email protected] Dr. Aileen Helsel on Social MediaLinkedIn: https://www.linkedin.com/in/aileenhelsel/Carilion Clinic: https://www.carilionclinic.org/Roanoke Blacksburg Innovation Alliance: https://rbia.tech/Director & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.comExecutive Producer: David Chen, Managing Director & Instructor of Engineering Design, UVASenior Producer: Hannah Moore, Associate Director, UVA CoulterDesign Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.comProduced on behalf of Wallace H. Coulter Center for Translational Research at University of Virginia https://engineering.virginia.edu/centers-institutes/coulter-center-translational-research

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• Tech Transfer, navigating the healthcare system and taking risks, from academia to industry with David Chen and Lisa Bowers

  How do groundbreaking biomedical innovations move from research labs to real-world applications? What challenges make healthcare such a complex industry for startups? What risks are worth taking when translating science into impactful solutions?In this episode host Dasha Tyshlek sits down with David Chen, Assistant Dean of Entrepreneurship and Innovation Partnerships, and Lisa Bowers, Director of UVA’s Enterprise Studio and former biotech executive, to explore tech transfer in healthcare. We discuss:Layers of complexity in solving healthcare challengesEconomic realities that make healthcare innovation difficultHow early-stage biotech companies navigate funding, regulations, and clinical trialsLisa and David share insights from their experiences in academia and industry, discussing how researchers can effectively bridge the gap between discovery and commercialization.Resources MentionedCVille BioHub: https://cvillebiohub.org/Manning Institute: https://manninginstitute.virginia.eduBuilding Better Medicine: https://buildingbettermedicine.comFollow David ChenLinkedIn: https://www.linkedin.com/in/david-c-3889753/UVA’s Wallace H. Coulter Center: https://engineering.virginia.edu/centers-institutes/coulter-center-translational-researchUVA’s School of Engineering and Applied Science: https://engineering.virginia.edu/Follow Lisa BowersLinkedIn: https://www.linkedin.com/in/lisavbowers/Medium: https://medium.com/@lisavbowersUVA’s Enterprise Studio: https://lvg.virginia.edu/enterprise-studio-1UVA’s Licensing and Ventures Group: https://lvg.virginia.edu/Follow usInstagram: @biomedicalfrontiersLinkedIn: https://www.linkedin.com/company/uvacoulterProduction Team:Director & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.comExecutive Producer: David Chen, Managing Director & Instructor of Engineering DesignSenior Producer: Hannah Moore, Associate Director, UVA CoulterDesign Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.comProduced on behalf of Wallace H. Coulter Center for Translational Research at University of Virginia

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• Dr. Ben Holmes on Regenerating Cartilage: A 3D Printed Future for Joint Health

  Cartilage doesn’t heal easily—but what if it could? In this episode, we sit down with Ben Holmes Ph.D, CEO of Nanochon, to explore how his team is revolutionizing cartilage repair with 3D printing technology. Learn how Nanochon’s innovative material mimics natural cartilage and stimulates proper healing and repair. It may one day make knee replacements obsolete. Ben also shares his leadership journey, how he conducted over 100 physician interviews to help him understand the pain points in orthopedics, and insights on leading technological disruption in medical practices and procedures.Love this podcast? Write to us with ideas, feedback, and guest recommendations at [email protected] Holmes is the CEO driving force behind Nanochon, a company innovating cartilage repair and regeneration. Holmes's expertise in biomedical engineering has positioned Nanochon as a frontrunner in developing next-generation orthopedic medical devices. Nanochon is creating durable, effective treatments for orthopedic patients, promising a future where advanced, reliable solutions are readily available to improve the quality of life for individuals with joint issues.Before founding Nanochon, Dr. Holmes was the CTO at SonoStik, another George Washington University medical device startup.He has a Bachelors of Science degree in mechanical engineering from UVA, and a PhD in Biomaterials and Nanomedicine from The George Washington University.Follow Dr. Ben Holmes on Social MediaLinkedIn: https://www.linkedin.com/in/bbhceo/Check out Nanochon: https://www.nanochon.com/Read about CVille Biohub's Annual BioSpark Competition: https://cvillebiohub.org/bio-spark/Learn about NSF's iCorp Program: https://new.nsf.gov/funding/initiatives/i-corpsMedTech Innovator is recruiting their next class - apply here: https://medtechinnovator.org/---------------------------------------------Director & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.comExecutive Producer: David Chen, Managing Director & Instructor of Engineering Design, UVASenior Producer: Hannah Moore, Associate Director, UVA CoulterDesign Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.comProduced on behalf of Wallace H. Coulter Center for Translational Research at University of Virginia https://engineering.virginia.edu/centers-institutes/coulter-center-translational-research

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• Dr. Jonathon Hill on Gene Sequencing: How Epigenetics is Driving New Diagnostics and Disease Prevention

  Genetic sequencing is the process of determining the exact order of the nucleotides in a DNA or RNA molecule. Sequencing provides the complete "blueprint" of an organism's genetic code, and it's a critical tool in genetics, molecular biology, and medical research. Dr. Jonathon Hill develops innovative genomic and bioinformatic methods for gene expression analysis which has tremendous applications in cancer, early detection of chronic diseases, and personalized medicineLove this podcast? Write to us with ideas, feedback, and guest recommendations at [email protected]. Jonathon Hill is an Associate Professor of Cell Biology and Physiology at Brigham Young University and the Vice President of Science & Technology at Wasatch Biolabs. In this episode of Biomedical Frontiers, we dive into the field of genetic sequencing and genomics, how Jonathon built a company from the foundation of a novel gene sequencing technique, his research into congenital heart defects, and the future of the epigenetics field.He is a Fulbright Scholar and a BYU Early-Career Teaching Award recipient, having received his MS in Molecular Biology from the University of Colorado Health Science Center and a PhD in Genetics and Developmental Biology from Columbia University. His company Wasatch Biolabs is working to move epigenetics from the lab to the clinic and his lab at BYU researches the molecular genetics of congenital heart defects by studying development of hearts in embryos. Follow Dr. Jonathon Hill on Social MediaLinkedIn: https://www.linkedin.com/in/jonathon-t-hill/Check out Dr. Jonathon Hill’s work at Wasatch Biolabs: https://www.wasatchbiolabs.com/Director & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.comExecutive Producer: David Chen, Managing Director & Instructor of Engineering Design, UVASenior Producer: Hannah Moore, Associate Director, UVA CoulterDesign Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.comProduced on behalf of Wallace H. Coulter Center for Translational Research at University of Virginia https://engineering.virginia.edu/centers-institutes/coulter-center-translational-research

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