566 episódios
- The most popular Python project you've probably never heard of has 252,000 GitHub stars and merged over 1,800 pull requests in a single week. It's Hermes, a self-hosted AI agent you program just by talking to it. And it never clocks out. It runs 24/7 on a box in your house, wakes up every 15 minutes, keeps your YouTube channel in sync, and has your morning briefing ready before you're up. Mine started as a few config files. A few months later, it's 16,000 files of skills, memories, and tools it built for itself, all while I wasn't watching. Jeff Triplett joins me to explore this honestly weird but kind of amazing world. And yes, Hermes has a few words for you, too.
Episode sponsors
Talk Python Membership
Talk Python Membership
Talk Python Courses
Links from the show
Talk Python Tech Talks: talkpython.fm/meetups
Hermes: github.com
Ollama cloud models: ollama.com
https\://hermes-agent.nousresearch.com: hermes-agent.nousresearch.com
Hermes Web UI: get-hermes.ai
built my own UI: blobs.talkpython.fm
the Hermes Dashboard: blobs.talkpython.fm
the audio from the chat example: blobs.talkpython.fm
the CLI: blobs.talkpython.fm
Tailscale: tailscale.com
Hindsight: hindsight.vectorize.io
trmnl display: trmnl.com
JEV: typesafe.ai
Home Assistant Green: www.home-assistant.io
QMD - Query Markup Documents: github.com
OrangePi: www.orangepi.org
Watch this episode on YouTube: youtube.com
Episode #567 deep-dive: talkpython.fm/567
Episode transcripts: talkpython.fm
Theme Song: Developer Rap
🥁 Served in a Flask 🎸: talkpython.fm/flasksong
---== Don't be a stranger ==---
YouTube: youtube.com/@talkpython
Bluesky: @talkpython.fm
Mastodon: @talkpython@fosstodon.org
X.com: @talkpython
Michael on Bluesky: @mkennedy.codes
Michael on Mastodon: @mkennedy@fosstodon.org
Michael on X.com: @mkennedy - Which of your Python tools would you still pick if you started fresh today? For a long time, the answer was easy. The stack felt settled. AI has reopened almost every one of those choices. Some tools got faster. Others got replaced outright. On this episode, a panel takes stock of the state of the art in Python for 2026. Calvin Hendryx-Parker is CTO and co-founder of Six Feet Up. Pat Decker works in DevOps at Hibu. Reuven Lerner has trained Python developers for 15 years. Sydney Runkle does product management for open source at LangChain. One of them barely opens an editor anymore. Listen in to hear the surprising replacement.
Episode sponsors
Talk Python Courses
Python in Production
Links from the show
Guests
Pat Decker
Reuven Lerner: github.com
Calvin Hendryx-Parker: linkedin.com
Sydney Runkle: github.com
Talk Python Membership: talkpython.fm/community
This Reddit post: www.reddit.com
PSF+Jetbrains survey: blog.jetbrains.com
vscode: code.visualstudio.com
pycharm: www.jetbrains.com
cmux: cmux.com
warp.dev: www.warp.dev
herdr: herdr.dev
Royal TS: apps.microsoft.com
Tailscale: tailscale.com
uv: docs.astral.sh
FastAPI: fastapi.tiangolo.com
Litestar: litestar.dev
Django: www.djangoproject.com
httpx2: github.com
ty: github.com
pyrefly: pyrefly.org
postgres: www.postgresql.org
sqlite: www.sqlite.org
duckdb: duckdb.org
Hetzner: www.hetzner.com
DigitalOcean: www.digitalocean.com
AWS: aws.amazon.com
Great Docs: posit-dev.github.io
Zensical: zensical.org
Vue.js: Vue.js
AgentsView: www.agentsview.io
LangChain Blog: www.langchain.com
Umami Example of Great Docs: mkennedy.codes
Mintlify: www.mintlify.com
DuckLake: ducklake.select
Robyn Web Framework: robyn.tech
Django Ninja: django-ninja.dev
Talk Python CLI: talkpython.fm
KEdit: www.kedit.com
Kitty: sw.kovidgoyal.net
Watch this episode on YouTube: youtube.com
Episode #566 deep-dive: talkpython.fm/566
Episode transcripts: talkpython.fm
Theme Song: Developer Rap
🥁 Served in a Flask 🎸: talkpython.fm/flasksong
---== Don't be a stranger ==---
YouTube: youtube.com/@talkpython
Bluesky: @talkpython.fm
Mastodon: @talkpython@fosstodon.org
X.com: @talkpython
Michael on Bluesky: @mkennedy.codes
Michael on Mastodon: @mkennedy@fosstodon.org
Michael on X.com: @mkennedy - Do you know what's actually slow in your Python app? Or are you guessing? Until now, profiling Python meant a tracing profiler that made your code 2 to 3 times slower. Or a third-party tool that broke with every new release. Python 3.15 fixes that. It ships Tachyon, a sampling profiler built into the standard library. It attaches to live production apps with almost zero overhead. My guests are Pablo Galindo Salgado, CPython core developer and Steering Council member, and László Kiss Kollár from Bloomberg's Python infrastructure team. Their first prototype ran at two samples a second. Now it does over a million hz. And it lands in Python 3.15 this October.
Episode sponsors
Sentry Error Monitoring, Code talkpython26
Python in Production
Talk Python Courses
Links from the show
Guests
László Kiss Kollár: linkedin.com
Pablo Galindo Salgado
3.11: talkpython.fm
Memray: talkpython.fm
PyStack: talkpython.fm
profile and cProfile: docs.python.org
py-spy: github.com
Austin: github.com
PEP 799: peps.python.org
PEP 768: peps.python.org
PyCon US 2026 talk: us.pycon.org
The docs: docs.python.org
Backport to 3.14: github.com
Watch this episode on YouTube: youtube.com
Episode #565 deep-dive: talkpython.fm/565
Episode transcripts: talkpython.fm
Theme Song: Developer Rap
🥁 Served in a Flask 🎸: talkpython.fm/flasksong
---== Don't be a stranger ==---
YouTube: youtube.com/@talkpython
Bluesky: @talkpython.fm
Mastodon: @talkpython@fosstodon.org
X.com: @talkpython
Michael on Bluesky: @mkennedy.codes
Michael on Mastodon: @mkennedy@fosstodon.org
Michael on X.com: @mkennedy - Every ship in EVE Online eventually undocks and leaves the station. This time, it's the whole game. EVE has run on Python 2 since it launched in 2003, all 2.4 million lines of it, on a custom Stackless interpreter that stopped at 3.8 and was archived last year. Destination: Python 3.12. The route runs through 6,500 lines of division that decide who wins a fight, and 100 gigabytes of pickled Python objects that have to survive the jump intact. Kristinn Sigurbergsson was on this show ten years ago. He's back, with Jamie Bannister, who is flying the EVE Online migration right now, and Thomas Dähling, who took EVE Frontier through first. In EVE, a destroyed ship is gone for good. There are no do-overs, and the universe has to stay online the whole way.
Episode sponsors
Sentry Error Monitoring, Code talkpython26
Talk Python Courses
Links from the show
Guests
Jamie Bannister: linkedin.com
Thomas Dähling: linkedin.com
Kristinn Sigurbergsson: linkedin.com
EVE Online: www.eveonline.com
EVE Frontier: evefrontier.com
2.4 million lines of Python: www.eveonline.com
Example of graphics, ships walk-through: www.youtube.com
Stackless: www.stackless.com
futurize: python-future.org
blue: github.com
Dev blog on the Frontier upgrade: evefrontier.com
Upgrading CARBON to Python 3: www.youtube.com
carbon-scheduler: github.com
Scheduling in Carbon: Leaving Stackless Python Behind: www.youtube.com
All of Carbon is on GitHub now: github.com
did a whole course: training.talkpython.fm
Trade Wars BBS (Wikipedia): en.wikipedia.org
TW 3002 - TradeWars 2002, reimagined as a modern browser game: www.reddit.com
Watch this episode on YouTube: youtube.com
Episode #564 deep-dive: talkpython.fm/564
Episode transcripts: talkpython.fm
Theme Song: Developer Rap
🥁 Served in a Flask 🎸: talkpython.fm/flasksong
---== Don't be a stranger ==---
YouTube: youtube.com/@talkpython
Bluesky: @talkpython.fm
Mastodon: @talkpython@fosstodon.org
X.com: @talkpython
Michael on Bluesky: @mkennedy.codes
Michael on Mastodon: @mkennedy@fosstodon.org
Michael on X.com: @mkennedy - Lint the entire CPython code base from scratch. It takes 0.3 seconds. Three blinks of an eye.
That is ruff, and it is written in Rust. So are Pydantic, Polars, uv, and Granian. Rust shows up in Python three ways: tools that happen to be Rust, libraries Python imports, and servers that run Python inside Rust. This is Rust for Python developers, not Rust experts.
Christopher Trudeau is back on Talk Python to discuss Rust and his latest course Up and Running with Rust. The core rule is that only one thing can own a value at a time. Pass it around freely in Python and the garbage collector cleans up. Do that in Rust and it will not compile.
Episode sponsors
Sentry Error Monitoring, Code talkpython26
Python in Production
Talk Python Courses
Links from the show
Up and Running with Rust course: training.talkpython.fm
Rust: rust-lang.org
pydantic: pydantic.dev
ruff: docs.astral.sh
granian: github.com
By example: doc.rust-lang.org
rust-lang.org: rust-lang.org
rustup.rs: rustup.rs
crates.io: crates.io
main.rs: main.rs
PyO3: github.com
https://github.com/ritwiktiwari/awesome-python-rs: github.com
ty: docs.astral.sh
pyrefly: pyrefly.org
uv: github.com
polars: pola.rs
Watch this episode on YouTube: youtube.com
Episode #563 deep-dive: talkpython.fm/563
Episode transcripts: talkpython.fm
Theme Song: Developer Rap
🥁 Served in a Flask 🎸: talkpython.fm/flasksong
---== Don't be a stranger ==---
YouTube: youtube.com/@talkpython
Bluesky: @talkpython.fm
Mastodon: @talkpython@fosstodon.org
X.com: @talkpython
Michael on Bluesky: @mkennedy.codes
Michael on Mastodon: @mkennedy@fosstodon.org
Michael on X.com: @mkennedy
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Talk Python to Me is a weekly podcast for Python developers, data scientists, and AI builders,
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quickly learn the ins and outs of the community by hearing from its leaders. And if you've been Pythoning
for years, you'll hear about your favorite packages and the hot new ones coming out of open source.
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