Brainforest Café

For nearly a century, reports of a mysterious psychoactive bolete have puzzled ethnomycologists and anthropologists alike. From the 1930s reports of "mushroom madness" in the highlands of Papua New Guinea, which drew the curiosity of R. Gordon Wasson, Roger Heim, and Albert Hofmann, to modern Yunnan, China, where accidental poisonings from undercooked culinary mushrooms cause people to reliably see visions of tiny, colorfully dressed "little people."

In this episode of The Brainforest Café, Dennis McKenna sits down with mycologist and PhD candidate Colin Domnauer (University of Utah) to discuss how modern genomics, natural product chemistry, and fieldwork cracked this long-standing mystery.

Colin shares his journey traveling to the markets and forests of Southwest China and the Philippines, using DNA sequencing to identify the primary species responsible (Lanmaoa asiatica), conducting groundbreaking rodent bioassays, and exploring what these non-psilocybin compounds could reveal about the neurobiology of perception and the cross-cultural phenomenon of Lilliputian hallucinations.

- - -

Colin is a Bay Area California native whose research focuses on unravelling the ethnomycological mystery of psychoactive bolete mushrooms. With a lifelong interest and undergraduate degree in astronomy before changing his studies to the ethnobiology of psychoactive substances, Colin has always felt attracted to explore the mind-bending wonders of nature. In his free time, he enjoys engaging in just about any outdoor activity with friends, most of all foraging for mushrooms.
Learn more about your ad choices. Visit megaphone.fm/adchoices

Dennis McKenna sits down with scholar, lawyer, and philosopher Tam Hunt (UC Santa Barbara’s META Lab) to dive deep into the mysteries of consciousness, psychedelics, and the existential crossroads of artificial intelligence.

Tam shares his unconventional journey, from growing up in a 1970s counterculture commune to transformative, high-dose LSD journeys in Waimea Canyon, and how these experiences led him to co-develop the General Resonance Theory (GRT) with Jonathan Schooler. Together, Dennis and Tam explore panpsychism, Whiteheadian process philosophy, the limits of reductionist neuroscience, plant intelligence, and whether future AI built on electromagnetic "field computing" could become conscious. They conclude with a candid discussion on AI safety, existential risk, the approaching 2030 Singularity, and why the principle of stewardship as love is essential for humanity's survival.
Learn more about your ad choices. Visit megaphone.fm/adchoices

Jonathan Dickinson, CEO and co-founder of Ambio Life Sciences and author of Ibogaine and the Bicameral Mind, returns to the Brainforest Café for part two of his conversation with Dr. Dennis McKenna. Where part one followed the personal journey, this one goes into the machinery: what ibogaine is actually doing to the mind and to the cell.

- - -

Jonathan Dickinson, co-founder and CEO of Ambio Life Sciences and
founder of Terragnosis, joins Dr. Dennis McKenna on the Brainforest Café
for a conversation about ibogaine, iboga, and the Bwiti tradition of
Gabon.

A Mexico-licensed psychologist and former executive director of
the Global Ibogaine Therapy Alliance, Jonathan helped develop the
field's foundational safety guidelines and completed the first
Nagoya-compliant export of Tabernanthe iboga root. In part one of a
two-part conversation, he traces the path from harm reduction work in
Vancouver's Downtown Eastside to initiation in Gabon, and explains why
ibogaine refuses to behave like a pharmaceutical. It does not reduce
symptoms. It opens a door, and the person has to walk through it.
Learn more about your ad choices. Visit megaphone.fm/adchoices

Jonathan Dickinson, co-founder and CEO of Ambio Life Sciences and
founder of Terragnosis, joins Dr. Dennis McKenna on the Brainforest Café
for a conversation about ibogaine, iboga, and the Bwiti tradition of
Gabon.

- - -

Jonathan Dickinson, a Mexico-licensed psychologist and former executive director of the Global Ibogaine Therapy Alliance, Jonathan helped develop the field's foundational safety guidelines and completed the first
Nagoya-compliant export of Tabernanthe iboga root. In part one of a
two-part conversation, he traces the path from harm reduction work in
Vancouver's Downtown Eastside to initiation in Gabon, and explains why
ibogaine refuses to behave like a pharmaceutical. It does not reduce
symptoms. It opens a door, and the person has to walk through it.
Learn more about your ad choices. Visit megaphone.fm/adchoices

What if the future of ayahuasca isn’t in the hype cycle, but in safety, tradition, and real transformation? In this conversation, Sam Believ and Dennis McKenna explore Colombia’s overlooked ayahuasca lineage, the importance of set and setting, and why plant medicine may hold a key to healing both people and culture.

- - -

Sam Believ is the founder of LaWayra Ayahuasca Retreat and host of the Ayahuasca Podcast.

​A former offshore engineer turned modern bridge-builder, Sam is dedicated to making traditional Amazonian medicine accessible, safe, and grounded for the modern world.

He build LaWayra - currently the biggest Ayahuasca retreat in Colombia, while raising 3 small kids all in 2 foreign languages and without any business background.

At LaWayra he has guided close to 3000 people through their Ayahuasca experience.
Learn more about your ad choices. Visit megaphone.fm/adchoices