Psychopharmacology and Psychiatry Updates

In this episode, we explore stimulant medications for adult ADHD with Dr. Oscar Bukstein. Why have amphetamines overtaken methylphenidate as the most prescribed option? Discover how to match formulation duration to patient needs, navigate cardiovascular risks, and monitor treatment effectively for optimal outcomes in adult ADHD management.
Faculty: Oscar G. Bukstein, M.D., M.P.H.
Host: Richard Seeber, M.D.
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Earn 0.75 CME: Mastering Adult ADHD: A Comprehensive Clinical Guide
Pharmacologic Treatments for Adult ADHD: Focus on Stimulants

In this episode, we explore the groundbreaking COaST trial examining semaglutide for clozapine-induced weight gain in schizophrenia patients. Could GLP-1 agonists finally offer a real solution to one of psychiatry's most frustrating paradoxes—when the medication that saves lives simultaneously shortens them?
Faculty: Oliver Freudenreich, M.D.
Host: Richard Seeber, M.D.
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Earn 0.5 CMEs: Quick Take Vol. 78
Does Semaglutide Reverse Clozapine-Induced Weight Gain in Schizophrenia? Results from the COaST Trial

In this episode, we explore the treatment algorithm for adult ADHD with Dr. Oscar Bukstein from Harvard Medical School. Should you start with stimulants or non-stimulants when substance use disorder complicates the picture? Discover how comorbidities like depression and anxiety reshape your medication selection strategy for optimal patient outcomes.
Faculty: Oscar G. Bukstein, M.D., M.P.H
Host: Richard Seeber, M.D.
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Earn 0.75 CME: Mastering Adult ADHD: A Comprehensive Clinical Guide
Treatment Algorithm for Adult ADHD

In this episode, we explore pramipexole—a Parkinson's medication—as a promising add-on treatment for treatment-resistant bipolar depression. Could a dopamine agonist be the unexpected solution when standard mood stabilizers and antipsychotics fail? We examine the PAX-BD trial's findings, safety concerns, and practical clinical applications.
Faculty: Kristin Raj, M.D.
Host: Richard Seeber, M.D.
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Earn 0.5 CME: Quick Take Vol. 78
Treatment-Resistant Bipolar Depression: Is Adjunctive Pramipexole An Option?

In this episode, we explore the controversial role of SERT gene testing in predicting SSRI response with Dr. Chris Aiken. Can genetic testing really tell us which patients will respond to antidepressants, or are we putting too much faith in pharmacogenetic promises that lack solid evidence?
Faculty: Chris Aiken, M.D.
Host: Richard Seeber, M.D.
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Earn 0.75 CME: The Role of Genetic Testing in Psychiatry
SERT Gene and SSRI Response: Is It Clinically Useful?