Dhru Purohit Show

• A Controversial Yet Promising Approach to Cancer: Is This The Future of Cancer Treatment?

  This episode is brought to you by Levels, Bon Charge, and Ollie, For years, many have believed that cancer is primarily genetic or just bad luck, but emerging research suggests we have far more control over our risk than previously thought. Dr. Thomas Seyfried's groundbreaking work reframes cancer as a metabolic dysfunction, focusing on its root cause rather than just treating symptoms. While controversial, this approach offers new hope for both practitioners and patients seeking alternative strategies for prevention and treatment. Today on The Dhru Purohit Show, we’re bringing you a special compilation episode featuring Dhru’s conversations with Dr. Thomas Seyfried and experts from the Hippocrates Research Foundation, a nonprofit dedicated to continuing Dr. Seyfried’s work by educating cancer patients on metabolic-based treatment approaches. Dr. Seyfried explores the role of oxidative stress, mitochondrial health, and glucose in cancer development and progression, along with his research on ketogenic diets as a promising solution to correct these imbalances. Den Stacey shares his journey of seeking guidance from the Hippocrates Research Foundation—ultimately becoming cancer-free. The Hippocrates Research Foundation team—Daniel Orrego, Dr. Gregory Howard, and Dr. Michelle Howard—discuss their research and their approach to guiding cancer patients by implementing a protocol designed to starve cancer while fueling the body. Dr. Thomas Seyfried is an American professor of biology, genetics, and biochemistry at Boston College. With over 150 peer-reviewed publications, his research focuses on the mechanisms driving cancer, epilepsy, and neurodegenerative diseases, as well as the role of calorie-restricted ketogenic diets in their prevention and treatment. He is the author of Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer and serves on the editorial boards of Nutrition & Metabolism, Neurochemical Research, Journal of Lipid Research, and ASN Neuro. In this episode, Dhru and his guests dive into: The role of mitochondrial dysfunction in cancer (04:05) The promise of the ketogenic diet and its impact on cells (09:58) How the ketogenic diet cuts off cancer’s fuel sources (20:37) Den Stacey’s email about his experience with Dr. Seyfried’s protocol (26:54) The Press-Pulse protocol used in Den’s treatment (30:25) The role of stress reduction as a key part of the protocol (35:31) The benefits of hyperbaric oxygen therapy (38:53) Why pharmaceutical drugs and diet should be used in concert (40:47) What an ideal cancer treatment team looks like (46:31) Testing and evaluating the protocol in real-world cases (56:39) Recognizing the success of the case study and the next steps (59:42) Final thoughts (01:02:01) Also mentioned: Full episode with Dr. Thomas Seyfried Full episode with Den Stacey This episode is brought to you by Levels, Bon Charge, and Ollie, Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link, levels.link/DHRU. Make moves on your metabolic health with Levels today.  Right now, BON CHARGE is offering my community 15% off; just go to boncharge.com/DHRU and use coupon code DHRU to save 15%. Want to give your dog the best in clean eating? Take the online quiz and introduce Ollie to your pet. Right now, Ollie is offering 60% off your first box of meals when you subscribe today! Just head to Ollie.com, use the code DHRU and you’ll get 60% off your first box of meals in your subscription. Learn more about your ad choices. Visit megaphone.fm/adchoices

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• Stress Can Actually Make Your Life Better. Here’s How and Why You Need to Reframe Your Relationship with Stress with Jeff Krasno

  This episode is brought to you by LMNT, Maui Nui, and Birch Living.  When we think of stress, we often associate it with something negative—something to avoid. Our modern culture has fostered an environment of persistent chronic stress, yet at the same time, we've also eliminated beneficial stress by designing a life of chronic ease. Today's guest joins us to explain why stress isn't just unavoidable—it’s essential for growth. Today on The Dhru Purohit Show, Dhru sits down with Jeff Krasno, CEO and co-founder of Commune, to explore the benefits of positive stress in our modern world. Jeff explains why chronic stress harms our health and longevity, while adaptive stress—like fasting and hot/cold exposure—has been key to human evolution and survival. He also shares how to evaluate your protocols, behaviors, and routines to ensure they keep you in balance. Jeff is the co-founder and CEO of Commune, a masterclass platform focused on personal and societal well-being, and the co-creator of Wanderlust, a global series of wellness events. He also hosts the Commune podcast. His latest venture, Good Stress: The Benefits of Doing Hard Things, expands on his personal story and wellness protocols. Drawing from over 400 podcast conversations and his own experiences, the book explores deliberate, self-imposed behaviors that enhance social, psychological, and physical well-being.  In this episode, Dhru and Jeff dive into: How chronic ease is leading to disease (00:37) How to befriend stress (5:44) Jeff’s personal journey and the health challenges that shaped him (09:50) Fasting, hunger, and stress—how they can benefit you (23:34) Fasting recommendations for women and the importance of an individualized approach (26:50) Jeff’s Substack insights on weight loss (32:42) Research on cold plunges, blood glucose, cancer, glutamate, immunotherapy, and more (36:50) The future of health, chronic disease, systemic issues, and the decline of public trust in health and food institutions (43:19) The impact of health podcasts, their practices, and how people are paying attention to new information (56:24) How to lean into stressful conversations—plus tips for tackling them (59:18) Evaluating our protocols, behaviors, and routines—do they help us find balance and return to center (1:19:50) Final thoughts (1:24:45) Also mentioned in this episode: Jeff’s new book - Good Stress: The Health Benefits of Doing Hard Things Commune Podcast  Gabor Mate - Kiyumi retreat Thomas Seyfried's glutamate research KetoPet Sanctuary For more on Jeff, follow him on Facebook, Instagram, X/Twitter, Pinterest, YouTube, and his Website. This episode is brought to you by LMNT, Maui Nui, and Birch Living. Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to drinkLMNT.com/dhru today. Right now Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products. Just go to mauinuivenison.com/dhru to secure your access now —but hurry, supply is limited! To get 20% off your Birch Living mattress plus two free eco-rest pillows, head over to birchliving.com/dhru today. Learn more about your ad choices. Visit megaphone.fm/adchoices

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  1:28:06
• How to Minimize Toxic Exposure to Keep Our Children and Ourselves Healthy

  This episode is brought to you by Cozy Earth, One Skin, and Ollie. Environmental toxins are everywhere in our modern world—yet most remain untested for their long-term health effects or combined impact. With exposure at an all-time high, understanding how to minimize risk is more important than ever.  Today on The Dhru Purohit Show, we’re bringing you a special compilation episode featuring Dhru’s conversations with top experts on the toxins we encounter daily—and how to protect ourselves and our children. In this episode, our guests share practical strategies to reduce exposure and safeguard long-term health. Beth Lambert explores the growing epidemic of childhood disease linked to toxin exposure. She shares her personal journey of healing her children, the insights she uncovered along the way, the key factors affecting gut health, and how small changes can lead to big results. Dr. Joel breaks down the major drivers behind this rise, including ultra-processed foods and environmental toxins. He also introduces his SEEDS protocol—a holistic approach focused on both prevention and treatment. Beth Lambert is an Author, educator, and former healthcare consultant. She is also the Founder and Executive Director of Documenting Hope, a 501(c)(3) nonprofit organization that focuses on root-cause healing solutions for children’s chronic health and developmental issues. She has monitored and documented the escalating rates of childhood chronic conditions for 15 years.  Dr. Joel Warsh is a Board-Certified Pediatrician in Los Angeles, California who specializes in Parenting, Wellness and Integrative Medicine. He completed his Pediatric Medicine training at Children’s Hospital of Los Angeles (CHLA) and worked in private practice in Beverly Hills before founding his current practice, Integrative Pediatrics and Medicine Studio City, in 2018. In this episode, Dhru and his guests dive into: The role of the gut microbiome in detoxification (01:40) Multigenerational changes to environmental toxins and changes to our food systems  (11:40) Simple decisions that impact our overall health (22:54) Toxins in our everyday products and how to minimize exposure (25:59) What to prioritize to reduce toxic exposure, filtering water, and organic food (28:34) Toxins and the correlation between heavy metal exposure and Autism (35:44) Avoiding heavy metal exposure, testing, and diversity in food sources (38:19) Dr. Joel’s SEEDS protocol (44:21) Dhru’s Final Thoughts (51:34) Also mentioned: Full episode with Beth Lambert Full episode with Dr. Joel G. Warsh Parenting at Your Child's Pace: The Integrative Pediatrician’s Guide to the First Three Years Dr. Yvonne Burkart Episode: Toxicologist Reveals the Top Sources of Hidden Toxins We’re Being Exposed to Daily This episode is brought to you by Cozy Earth, One Skin, and Ollie.  Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com/dhru and use code DHRUP. Right now, One Skin is offering my community 15% off; just go to oneskin.co and use coupon code DHRU to save 15% and give your skin the scientifically proven, gentle care it deserves. Want to give your dog the best in clean eating? Take the online quiz and introduce Ollie to your pet. Right now, Ollie is offering 60% off your first box of meals when you subscribe today! Just head to Ollie.com, use the code DHRU and you’ll get 60% off your first box of meals in your subscription. Learn more about your ad choices. Visit megaphone.fm/adchoices

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• Supercharge Your Sleep and Improve Your Longevity Using the Power of Intermittent Fasting & Circadian Biology (Rebroadcast)

  This episode is brought to you by  Bon Charge and Momentous. We used to think circadian rhythm only applied to sleep. But emerging science has revealed a link between our circadian rhythm and metabolism, cognition, risk for chronic diseases, and many other crucial aspects of our health. Our biology was designed to live in sync with a natural light-dark cycle, but modern-day society has disrupted this natural balance.  Today on The Dhru Purohit Show, we’re revisiting one of our favorite episodes with Dr. Satchin Panda. Dr. Panda dives deep into his groundbreaking circadian biology research and shares how leveraging your circadian rhythm can dramatically improve your sleep, lower your risk of chronic disease, and improve your cognitive function. They also discuss how time-restricted eating, exercise, and light can be used to help program your circadian rhythm and why it’s especially important for shift workers to take advantage of these tools.  Dr. Panda is pioneering circadian biology research. He is a professor at the Salk Institute for Biological Studies, a Pew Biomedical Scholar, founder of the UC San Diego Center for Circadian Biology, and recipient of the Julie Martin Mid-Career Award in Aging Research. Dr. Panda has spoken at conferences around the world about his work on circadian rhythms and diabetes, including Diabetes UK, the American Diabetes Association, the Danish Diabetes Association, and the professional diabetes societies of Europe and Australia. In this episode, Dhru and Dr. Panda dive into: Why late-night eating is so detrimental to our health (2:15) Organ systems that have a circadian rhythm (8:24) Common ailments that could be related to circadian rhythm disturbances (14:11) Night-shift work and cancer risk (20:19) How poor sleep perpetuates bad food choices (27:00) What happens in the body when you rely on an alarm clock (44:01) Why you need to accumulate sleep debt for better sleep (51:25) Time-restricted eating and sleep (1:00:40) How to combat fragmented sleep (1:15:35) The best time to work out (1:55:50) The link between exercise and cancer (2:07:55) Positive changes for better sleep health on a global scale (2:17:20) Strategies for night-shift workers to combat circadian rhythm disruption 02:45:10) Dr. Panda’s research in firefighters (2:48:46) Tips for optimizing your circadian rhythm (3:14:20) Where to follow and support Dr. Panda's work (3:27:50) Also mentioned in this episode: The Circadian Code: Lose Weight, Supercharge Your Energy, and Transform Your Health from Morning to Midnight The Circadian Diabetes Code: Discover the Right Time to Eat, Sleep, and Exercise to Prevent and Reverse Prediabetes and Diabetes Download the MyCircadianClock app Try This: 6 Crazy Facts About Sleep Try This: How Exercise Helps Fight Cancer For more on Dr. Satchin Panda, follow him on Twitter @SatchinPanda, Instagram @satchin.panda, or his Website. This episode is brought to you by Bon Charge and Momentous. Right now, BON CHARGE is offering my community 15% off; just go to boncharge.com/DHRU and use coupon code DHRU to save 15%. Optimize your energy and mental clarity with the Momentous Three: Protein, Omega-3s, and Creatine made by and used by the best. Go to livemomentous.com and enter promo code DHRU to get 20% off any order.  Learn more about your ad choices. Visit megaphone.fm/adchoices

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  3:31:09
• Don't Let The Scale Run Your Life: The Power of Focusing on Body Composition

  This episode is brought to you by Fatty15 and Blueland. When it comes to weight loss, most people rely on the usual strategies—cutting calories and exercising more. But what happens when these methods don’t work? And how do we ensure we’re losing fat, not muscle? It’s time to rethink our approach. Instead of just focusing on the number on the scale, we should prioritize body recomposition—building a stronger, healthier body that supports longevity and resilience as we age. Today on The Dhru Purohit Show, we bring you a special compilation episode featuring Dhru's conversations with leading experts on why body composition is more important than your scale weight.  Sal Di Stefano, Mind Pump co-founder and fitness expert, explains why body composition matters more than the number on the scale. He breaks down the most efficient and sustainable ways to exercise and highlights the crucial role muscle plays in overall health. Sal also reveals why lasting motivation for a healthier lifestyle must come from within. By adopting practical, sustainable strategies, we can boost energy, improve well-being, and achieve our fitness goals—all while promoting longevity. JJ Virgin shares her top strategies for weight loss, muscle building, and vibrant aging, emphasizing the power of resistance training for sustained fat loss and the importance of tracking personal goals for long-term motivation. Sal Di Stefano began his fitness journey at just 18, quickly rising to prominence as a trainer and opening some of the largest big-box gyms in the California Bay Area. By 24, he launched a wellness-focused fitness studio that combined expertise in hormones, nutrition, gut health, and fitness training. Today, Sal is a highly sought-after expert known for his practical, easy-to-apply insights. As co-host of the Mind Pump Podcast—the world’s top fitness and health podcast—he’s appeared on hundreds of leading shows and frequently speaks at events for trainers and health practitioners. JJ Virgin is a renowned health and fitness expert, bestselling author, and prominent media personality. With over three decades of experience in the field, she has become a trusted authority in nutrition, weight loss, and wellness. She is the author of four New York Times bestsellers. Virgin actively contributes to the health and wellness community through speaking engagements, online programs, and her podcast, Well Beyond 40.  In this episode, Dhru and his guests dive into: Why weight loss matters less than body composition (1:08) Reframing our approach to exercise and the body's adaptation to fitness (12:41) Hacks to help with fat loss versus weight loss (22:43) Tracking movement and progress (26:10) Testing body composition and the importance of prevention (29:27) Tracking food intake to optimize protein, fiber, and sleep quality (33:09) Aging powerfully and the new normal (44:01) The misconception about bulking up and the reality of muscle building (47:56) Also mentioned: Full episode with Sal Di Stefano Full episode with JJ Virgin Virginia MacColl Oldest Ninja Warrior episode This episode is brought to you by Fatty15 and Blueland. Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health. Get a clean home while keeping a clean planet with Blueland. Right now, get 15% off your first order by going to blueland.com/dhru. Learn more about your ad choices. Visit megaphone.fm/adchoices

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