Intelligence Squared

Demis Hassabis – CEO and co-founder of Google DeepMind – is one of the world’s most visionary technologists. A child chess prodigy from North London, Hassabis was awarded the 2024 Nobel Prize in Chemistry for using artificial intelligence to predict the complex structures of nearly all known proteins. His company DeepMind, now owned by Google, is at the forefront of the pursuit to build artificial general intelligence, and considered Google’s engine room of AI innovation. 

Sebastian Mallaby – former FT contributing editor, two-time Pulitzer Prize finalist and author of numerous books – has, for the past 3 years, explored the moral questions at the heart of AI and AGI, through the story of Demis Hassabis. With extensive access to DeepMind and its key players, Mallaby has conducted hundreds of hours of interviews with Hassabis and his inner circle as well as detractors and rivals at other companies. No other journalist has had such a closeup view of the opportunities, hype and threats AI could pose for us all. 

In April 2026 Hassabis and Mallaby came together for an intimate exploration of The Infinity Machine, Mallaby’s definitive account of Hassabis’ life and career. They discussed how he came to lead the world’s most ambitious AI lab, what the pursuit of AGI might cost as well as  what it might unlock, and what the story of Hassabis and DeepMind can tell us about humanity’s innate drive to develop new technologies.
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Chemistry is everywhere. From cosmetics and the clothes we wear to life-saving medicines and kitchen experiments, chemical processes are all around us, defining our interactions with the world we live in. 

In this episode, Professor Dame Ijeoma Uchegbu joins Professor Helen Czerski to discuss how chemistry shapes our understanding of the world. Their conversation explores our complex relationship with plastics; the fact that synthetic products are not always harmful and natural ones not always safe; and the ways machine learning could transform chemical testing and revolutionise the development of new medicines.

Professor Dame Ijeoma Uchegbu is President of Wolfson College, University of Cambridge. She is the author of Chain Reaction: The Wondrous Chemistry of Everyday Life.

Professor Helen Czerski is a British physicist, oceanographer, and broadcaster.

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The Cambridge Five - Donald Maclean, Guy Burgess, Kim Philby, John Cairncross and Keeper of the Queen's Pictures Anthony Blunt - made up one of the most notorious spy rings of the 20th century. Besotted with communist ideology and radicalised while at Cambridge University in the 1930s, their clandestine supply of British and US intelligence material gave Stalin an inside track on US and British decision-making until May 1951.

So how did this collective come into being, what brought about its downfall, and why did four of the five never answer for their crimes?

In this episode, Antonia Senior draws on recently declassified files to reexamine the story of the Cambridge Five. Discussing her new book Stalin’s Apostles: The Cambridge Five and the Making of the Soviet Empire with historian and philosopher Sophie Scott Brown, Senior explores how a generation shaped by the crises of the 1930s was drawn to communism, and how elite networks within Cambridge and the British establishment enabled one of the most damaging intelligence breaches in modern history.

Antonia Senior is a journalist and writer. She is the author of Stalin’s Apostles: The Cambridge Five and the Making of the Soviet Empire.

Sophie Scott Brown is a historian and philosopher specialising in modern intellectual history and political thought.

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Our changing climate is accelerating conflict and migration, with the potential to drive political instability from the Sahel to Saudi Arabia to Siberia. From the water-stressed mountains of the Arabian Peninsula to the wildfires raging through America’s most populated regions, the climate crisis is already affecting the lives of millions. 

In a new book, Elemental, former diplomat Arthur Snell explores how global powers must adapt to new vulnerabilities, the risk of future conflicts over natural resources, and the links between the climate crisis and the rise of populism in Europe and the United States.

In this episode, he speaks to journalist Adam McCauley about our rapidly changing geopolitics, the technologies available to help us adapt to a heating planet, the potential for new forms of political cooperation and the choices we need to make to avert disaster.

Arthur Snell is a former British diplomat who has worked in Afghanistan, Iraq and Yemen. His new book is Elemental: The New Geography of Climate Change and How We Survive It. 

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More people are being labelled with medical conditions than ever before. Diagnoses of autism, ADHD, allergies, and long COVID have skyrocketed - but are we actually getting less healthy? 

In this episode, neurologist Dr Suzanne O’Sullivan speaks to Dr Güneş Taylor about an impending crisis of overdiagnosis. Drawing on histories of real people, as well as decades of clinical practice and the latest medical research, O’Sullivan argues her research indicates that ordinary life experiences, bodily imperfections, sadness and social anxiety are being subsumed into the category of medical disorder. In other words: we are not getting sicker – we are attributing more to sickness.

Dr Suzanne O’Sullivan is a neurologist and writer. She is the author of The Age of Diagnosis, as well as previous books including It’s All in Your Head and The Sleeping Beauties.

Dr Güneş Taylor is a science broadcaster and Fellow at the Centre for Reproductive Health.

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