School of Hard Knocks Podcast

Bob Duggan is a billionaire entrepreneur and investor best known for helping transform Pharmacyclics from a struggling biotech company into a cancer-treatment powerhouse that sold for $21 billion.

In this episode, Bob shares his journey from a modest childhood and early investing career to building businesses across food, robotics, healthcare, and pharmaceuticals. He opens up about losing his son to glioblastoma, how that experience shaped his commitment to medicine, and the principles behind his approach to risk, leadership, investing, responsibility, and wealth creation.

Find Bob Duggan here:
Website: https://robertduggan.com/
Genius Inc.: https://www.geniusinc.com/
LinkedIn: https://www.linkedin.com/in/robertwduggan
Pulse Biosciences: https://www.pulsebiosciences.com/
Summit Therapeutics: https://www.smmttx.com/overview/
Duggan Investments: https://www.dugganinvestmentsresearch.com/

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Kim Perell is a nine-time entrepreneur, angel investor in more than 100 companies, and the founder behind a business that grew from a $10,000 loan from her grandmother to a $235 million exit.

In this episode, Kim shares how she built through uncertainty, what she looks for when investing in early-stage founders, and the lessons she learned scaling companies from their first million toward nine-figure and billion-dollar outcomes.

She also breaks down mentorship, founder resilience, building valuable relationships, increasing a company’s attractiveness to buyers, and why focus matters more than diversification in the early years.

Kim closes with her philosophy on family, money, creativity, long-term thinking, and why no one becomes successful alone.

Find Kim Perell here:
Website: https://kimperell.com/
Instagram: https://www.instagram.com/kimperell/
LinkedIn: https://www.linkedin.com/in/kimperell/

Check out Kim’s books: https://kimperell.com/books/

Learn more about Juni: https://drinkjuni.com/

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Eddie Maalouf is the founder and CEO of BAD Marketing, an agency generating roughly $18 million annually, and an entrepreneur behind multiple businesses including Scoville Hot Chicken.

Before building his agency, Eddie became the top sales rep by volume at Lifetime Fitness and later helped generate an additional $1 million in profit for his family’s businesses.

In this episode, Eddie explains the sales systems, marketing strategies, hiring decisions, and organic content playbook that helped him scale from struggling to acquire clients to working with major brands including Yeezy. He also breaks down how he negotiated a restaurant business from a $1 million asking price to a $130,000 deal.

Follow Eddie Maalouf:
Instagram: instagram.com/eddiemaalouf

BAD Marketing: badmarketing.com

Scoville Hot Chicken: scovillechicken.com

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Jhalesa Seymour is the founder of Salt.XO, an eight-figure feminine hygiene brand generating more than $20 million annually, with one launch producing $1 million in just 30 minutes.

She started the company in college with only $67 and became the first millionaire in her family by age 25.

In this episode, Jhalesa shares how she created demand, built trust through organic marketing, survived a devastating 20,000-order fulfillment crisis, scaled with paid advertising, and learned to manage people and money through explosive growth.

She also discusses faith, motherhood, competition, building the right circle, and her ambition to turn Salt.XO into a global billion-dollar company.

Find Jhalesa Seymour here:
Instagram: https://www.instagram.com/jhalesa.xo/
Salt.XO: https://www.instagram.com/salt.xo/
Website: https://www.saltxo.com/

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Mike Wystrach is the founder of Freshly, the prepared-meal company acquired by Nestlé in 2020 in a deal valued at $1.5 billion. Before Freshly, Mike experienced business failure, lost his home, faced a $1 million judgment, and at 35 had just $15 in his bank account.

In this episode, he explains how he rebuilt his mindset, scaled Freshly to more than 1 million meals per week, navigated fundraising and hypergrowth, and ultimately decided to sell the business. Mike also shares lessons on entrepreneurship, customer obsession, building great teams, wealth, failure, and what he is building today through Petfolk and Cutting Horse.

Find Mike Wystrach here:
Website: https://mikewystrach.com/
Instagram: https://www.instagram.com/mikewystrach/
LinkedIn: https://www.linkedin.com/in/michaelwystrach/

Check out Mike’s businesses:
Petfolk: https://petfolk.com/
Cutting Horse: https://www.cuttinghorse.com/
Listen to The Advantage: https://mikewystrach.com/podcast/ https://mikewystrach.com/newsletter/

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